Cardiac Damage and Associated Consequences

Introduction

 The purpose of this program is to coordinate basic and clinical research aimed at understanding and treating myocardial damage and associated consequences. It includes all diseases caused by genetic or acquired disorders of the cardiac muscle.

Lines of research

The research in this program is organized into three main lines:

1) Myocardial Healing and Remodelling. The objective of this line is to clarify the molecular, structural, and functional mechanisms of cardiac tissue healing and the processes of atrial and ventricular remodelling. The new knowledge generated can be applied to develop, evaluate and validate advanced innovative therapies both in the pre-clinical setting and in the clinical setting.

2) Genetic Myocardial Damage. The objective of this line is to increase our knowledge of genetic cardiomyopathies and channelopathies in order to improve the effectiveness of current and novel treatments.

3) Heart Failure. The objective of this line is to prevent and effectively treat heart failure in order to improve patient quality of life and to reduce the incidence of the disease and the associated costs to the health system.

Program Coordinators

Research Groups